Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399846 | 0.90 | CASP3 (0.41) | ABCG2LTB4RLTB4R2CASP3SENP8 | |
| SCHEMBL717422 | 0.86 | DGAT1 (0.33) | L3MBTL1 | |
| SCHEMBL720091 | 0.84 | GABRA1 (0.39) | ABCG2LTB4RLTB4R2CASP3SENP8 | |
| SCHEMBL718396 | 0.80 | DGAT1 (0.37) | NPC1RAB9AMCHR1 | |
| SCHEMBL720636 | 0.80 | CASP3 (0.44) | ABCG2LTB4RLTB4R2CASP3SENP8 | |
| SCHEMBL718731 | 0.78 | CASP3 (0.46) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL719544 | 0.76 | CASP3 (0.40) | LTB4RLTB4R2CASP3SENP8SENP7 | |
| SCHEMBL719948 | 0.74 | CASP3 (0.41) | ABCG2LTB4RLTB4R2CASP3SENP8 | |
| SCHEMBL718680 | 0.74 | KDM4E (0.34) | NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL717066 | 0.74 | CASP3 (0.45) | ABCG2LTB4RLTB4R2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | ABCG2 893/4885LTB4R 1698/4885LTB4R2 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.