Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189294 | 0.90 | PTPN1 (0.31) | ALDH1A1 | |
| SCHEMBL7200760 | 0.75 | — | — | |
| SCHEMBL7189289 | 0.75 | PTPN1 (0.52) | — | |
| SCHEMBL7187611 | 0.75 | CD274 (0.39) | ALDH1A1 | |
| SCHEMBL7183224 | 0.74 | CYP2D6 (0.36) | — | |
| SCHEMBL7184328 | 0.73 | CYP1A2 (0.45) | ALDH1A1 | |
| SCHEMBL7185652 | 0.71 | MAPT (0.32) | ALDH1A1 | |
| SCHEMBL7599756 | 0.70 | PTPN1 (0.39) | ALDH1A1 | |
| SCHEMBL7187791 | 0.70 | SMN1; SMN2 (0.39) | ALDH1A1 | |
| SCHEMBL7194655 | 0.69 | PKM (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268494-A1 | SULFUR SUBSTITUTED ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS AS PTP-1B INHIBITORS | Merck Frosst Canada & Co. (CA) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070753-A1 | SULFUR SUBSTITUTED ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS AS PTP-1B INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2001-09-27 | — | — | WO | disclosed |