Sugi Predict

Sugi Predict / Compounds / SCHEMBL7189399

SCHEMBL7189399

SCHEMBL7189399

Cc1cc(C)c(C(=O)C(C(=O)OC(C)(C)C)c2ccccc2)c(C)c1.O=[PH3]

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.38
▸ MMP8 P22894 1/20 0.36
▸ LMNA P02545 4/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ ATM Q13315 1/20 0.35
▸ SLC6A2 P23975 2/20 0.35
▸ SLC6A4 P31645 2/20 0.35
▸ SLC6A3 Q01959 2/20 0.35
▸ GAA P10253 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ SRC P12931 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.33
▸ AAK1 Q2M2I8 1/20 0.33
▸ CTSS P25774 1/20 0.33
▸ CTSK P43235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27554196 0.96 L3MBTL1 (0.38) L3MBTL1MMP8LMNAKMT2AATM
SCHEMBL7181823 0.91 L3MBTL1 (0.37) L3MBTL1MMP8LMNAKMT2AATM
SCHEMBL7187383 0.89 L3MBTL1 (0.46) L3MBTL1MMP8LMNAKMT2AATM
SCHEMBL7183225 0.87 L3MBTL1 (0.36) L3MBTL1MMP8LMNAKMT2AATM
SCHEMBL27486004 0.86 L3MBTL1 (0.46) L3MBTL1MMP8LMNAKMT2AATM
SCHEMBL7177876 0.85 KMT2A (0.46) L3MBTL1MMP8LMNAKMT2ASLC6A2
SCHEMBL7183564 0.84 MMP8 (0.54) L3MBTL1MMP8KMT2AATMSLC6A2
SCHEMBL7180176 0.83 L3MBTL1 (0.38) L3MBTL1MMP8LMNAKMT2ASLC6A2
SCHEMBL14781389 0.81 SRC (0.47) L3MBTL1MMP8LMNAKMT2ASLC6A2
SCHEMBL7175796 0.81 L3MBTL1 (0.41) L3MBTL1MMP8LMNAKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 L3MBTL1 302/4885MMP8 4404/4885LMNA 3241/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 L3MBTL1 126/4885MMP8 4586/4885LMNA 3247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.