Sugi Predict

Sugi Predict / Compounds / SCHEMBL7189925

SCHEMBL7189925

SCHEMBL7189925

Cc1cc(C)c(C(=O)P(=O)(CCC(C)C)c2ccccc2)c(C)c1C

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.49
▸ POLB P06746 2/20 0.35
▸ MMP1 P03956 3/20 0.33
▸ MMP3 P08254 3/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ CFTR P13569 1/20 0.33
▸ MMP2 P08253 1/20 0.32
▸ MMP7 P09237 1/20 0.32
▸ MMP9 P14780 1/20 0.32
▸ MMP8 P22894 1/20 0.32
▸ P2RX7 Q99572 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180632 0.86 ALDH1A1 (0.38) ALDH1A1POLBMMP1MMP3SMN1; SMN2
SCHEMBL7189196 0.86 ALDH1A1 (0.55) ALDH1A1POLBMMP1MMP3SMN1; SMN2
SCHEMBL7181593 0.85 ALDH1A1 (0.53) ALDH1A1POLBMMP1MMP3SMN1; SMN2
SCHEMBL7181033 0.85 LMNA (0.40) ALDH1A1POLBSMN1; SMN2KMT2AMEN1
SCHEMBL7189448 0.83 ALDH1A1 (0.48) ALDH1A1POLBMMP1MMP3KMT2A
SCHEMBL7175020 0.83 TSHR (0.40) POLBKMT2AMEN1CFTRTSHR
SCHEMBL7180916 0.82 MEN1 (0.38) ALDH1A1POLBSMN1; SMN2KMT2AMEN1
SCHEMBL7176008 0.82 CETP (0.41) ALDH1A1POLBKMT2AMEN1TSHR
SCHEMBL7187862 0.81 CETP (0.43) ALDH1A1MMP1MMP3TSHR
SCHEMBL7183747 0.81 CETP (0.43) ALDH1A1MMP1MMP3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ALDH1A1 3416/4885POLB 2322/4885MMP1 4712/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ALDH1A1 3984/4885POLB 2993/4885MMP1 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.