Sugi Predict

Sugi Predict / Compounds / SCHEMBL7180632

SCHEMBL7180632

SCHEMBL7180632

Cc1cc(C)c(C(=O)P(=O)(CC(C)C)c2ccccc2)c(C)c1C

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.38
▸ MMP1 P03956 5/20 0.35
▸ MMP3 P08254 5/20 0.35
▸ POLB P06746 2/20 0.33
▸ MMP2 P08253 1/20 0.33
▸ MMP7 P09237 1/20 0.33
▸ MMP9 P14780 1/20 0.33
▸ MMP8 P22894 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ USP2 O75604 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ KDM4E B2RXH2 3/20 0.32
▸ MAPT P10636 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ ANPEP P15144 1/20 0.31
▸ LAP3 P28838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7189925 0.86 ALDH1A1 (0.49) ALDH1A1MMP1MMP3POLBMMP2
SCHEMBL7177532 0.86 ALDH1A1 (0.43) ALDH1A1MMP1MMP3POLBMMP2
SCHEMBL7183699 0.85 TSHR (0.32) ALDH1A1TSHRMEN1KMT2A
SCHEMBL7185540 0.84 ALDH1A1 (0.41) ALDH1A1MMP1MMP3POLBMMP2
SCHEMBL7180916 0.84 MEN1 (0.38) ALDH1A1POLBTSHRL3MBTL1USP2
SCHEMBL7175201 0.82 ALDH1A1 (0.37) ALDH1A1MMP1MMP3TSHRMEN1
SCHEMBL7183571 0.82 LMNA (0.38) ALDH1A1TSHRL3MBTL1USP2MEN1
SCHEMBL7181033 0.82 LMNA (0.40) ALDH1A1POLBTSHRL3MBTL1USP2
SCHEMBL7174987 0.80 ALDH1A1 (0.41) ALDH1A1POLBTSHRL3MBTL1MEN1
SCHEMBL7185570 0.80 ALDH1A1 (0.33) ALDH1A1MMP1MMP3POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ALDH1A1 3416/4885MMP1 4712/4885MMP3 4338/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ALDH1A1 3984/4885MMP1 4821/4885MMP3 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.