SCHEMBL7189937

SCHEMBL7189937

Oc1ccc(Sc2ccccc2Cl)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.48
RHEB Q15382 2/20 0.47
ALDH1A1 P00352 2/20 0.40
HDAC3 O15379 1/20 0.39
EP300 Q09472 1/20 0.39
KAT2B Q92831 1/20 0.39
KAT8 Q9H7Z6 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 1/20 0.38
PLA2G1B P04054 1/20 0.38
HSP90AA1 P07900 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11261233 0.86 IDO1 (0.65) IDO1HDAC3EP300KAT2BKAT8
SCHEMBL7191375 0.79 CYP1A2 (0.54) IDO1ALDH1A1HDAC3EP300KAT2B
SCHEMBL11125922 0.78 ALDH1A1 (0.54) RHEBALDH1A1MEN1PLA2G1BHSP90AA1
SCHEMBL6915666 0.77 RHEB (0.55) RHEBALDH1A1KDM4ENPSR1RXFP1
SCHEMBL29543966 0.77 RHEB (0.55) RHEBALDH1A1KDM4ENPSR1RXFP1
SCHEMBL9400360 0.76 IDO1 (0.46) IDO1RHEBALDH1A1HDAC3EP300
SCHEMBL7540795 0.76 PKM (0.52) RHEBALDH1A1KDM4ENPSR1RXFP1
SCHEMBL7196187 0.75 USP2 (0.50) IDO1ALDH1A1KDM4EMEN1CYP2C9
SCHEMBL30548744 0.75 RHEB (0.53) RHEBALDH1A1KDM4ENPSR1RXFP1
SCHEMBL7196033 0.75 IDO1 (0.54) IDO1HDAC3EP300KAT2BKAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 IDO1 2046/4885RHEB 1667/4885ALDH1A1 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.