SCHEMBL7189976

SCHEMBL7189976

Cc1cc(Sc2ccc(N)cc2)ccc1N

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.58
TSHR P16473 3/20 0.58
MAPK1 P28482 2/20 0.58
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ANXA2 P07355 1/20 0.44
S100A10 P60903 1/20 0.44
HTT P42858 1/20 0.41
CASP1 P29466 1/20 0.41
PDE7A Q13946 2/20 0.41
GCK P35557 1/20 0.39
S100B P04271 1/20 0.37
ACHE P22303 1/20 0.37
SKP2 Q13309 1/20 0.36
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31457312 1.00 CYP3A4 (0.58) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL273206 0.91 CYP3A4 (0.54) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL11354311 0.86 GCK (0.47) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL11455389 0.85 CYP3A4 (0.61) CYP3A4TSHRMAPK1ALDH1A1MAPT
SCHEMBL20565650 0.84 CYP3A4 (0.45) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL7195456 0.82 CYP3A4 (0.42) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL7184598 0.81 PDE7A (0.44) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL7192026 0.81 ALDH1A1 (0.43) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL10597213 0.81 CYP3A4 (0.61) CYP3A4TSHRMAPK1ALDH1A1TDP1
SCHEMBL7869707 0.80 CYP3A4 (0.67) CYP3A4TSHRMAPK1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111345-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2021-09-07 US disclosed
US-20170327657-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2017-11-16 US disclosed
US-9765194-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2017-09-19 US disclosed
EP-2878617-B1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2017-03-01 EP disclosed
US-9470058-B2 Ultra high temperature packer by high-temperature elastomeric polymers SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2016-10-18 US disclosed
US-20150210813-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2015-07-30 US disclosed
EP-2878617-A1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2015-06-03 EP disclosed
US-20110139466-A1 ULTRA HIGH TEMPERATURE PACKER BY HIGH-TEMPERATURE ELASTOMERIC POLYMERS SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2011-06-16 US disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed