SCHEMBL7192026

SCHEMBL7192026

Cc1cc(N)cc(Sc2ccc(N)c(C)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.43
TSHR P16473 4/20 0.43
CYP3A4 P08684 6/20 0.41
TDP1 Q9NUW8 6/20 0.41
MAPK1 P28482 3/20 0.35
ALOX15 P16050 4/20 0.33
THRB P10828 2/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GCK P35557 1/20 0.33
S100B P04271 1/20 0.33
SKP2 Q13309 1/20 0.33
CASP1 P29466 1/20 0.32
GAA P10253 3/20 0.32
RAD52 P43351 1/20 0.32
RECQL P46063 1/20 0.32
HIF1A Q16665 1/20 0.32
MAPT P10636 2/20 0.31
HSD17B10 Q99714 2/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273206 0.84 CYP3A4 (0.54) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL7187600 0.82 ALDH1A1 (0.63) ALDH1A1TSHRCYP3A4MAPK1ALOX15
SCHEMBL7188754 0.81 TSHR (0.58) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL7189976 0.81 CYP3A4 (0.58) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL31457312 0.81 CYP3A4 (0.58) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL7195456 0.80 CYP3A4 (0.42) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL7183466 0.78 ALDH1A1 (0.46) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL11947057 0.77 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4MAPK1SMN1; SMN2
SCHEMBL811095 0.76 NR1H2 (0.52) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL11354311 0.76 GCK (0.47) ALDH1A1TSHRCYP3A4TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111345-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2021-09-07 US disclosed
US-20170327657-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2017-11-16 US disclosed
US-9765194-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2017-09-19 US disclosed
EP-2878617-B1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2017-03-01 EP disclosed
US-20150210813-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2015-07-30 US disclosed
EP-2878617-A1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2015-06-03 EP disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed