SCHEMBL7189996

SCHEMBL7189996

CC(=O)N(C(C)=O)c1ccc(O)c2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.68
EP300 Q09472 3/20 0.58
KAT2B Q92831 3/20 0.58
KAT8 Q9H7Z6 3/20 0.58
IDO1 P14902 9/20 0.50
KDM4E B2RXH2 3/20 0.42
MAPT P10636 3/20 0.42
MEN1 O00255 1/20 0.42
NSD2 O96028 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
MCL1 Q07820 1/20 0.42
HDAC3 O15379 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
LDHA P00338 1/20 0.40
CTSB P07858 1/20 0.39
TP53 P04637 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CDC25B P30305 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25969103 0.89 GAA (0.81) GAAEP300KAT2BKAT8IDO1
SCHEMBL11565235 0.77 GAA (0.61) GAAKDM4EMAPTMEN1POLB
SCHEMBL9611559 0.76 EP300 (0.68) EP300KAT2BKAT8IDO1KDM4E
SCHEMBL10414646 0.75 EP300 (0.96) GAAEP300KAT2BKAT8IDO1
SCHEMBL11024265 0.74 GAA (0.77) GAAKDM4EMAPT
SCHEMBL25969099 0.74 GAA (0.53) GAAMAPTMEN1KMT2ALDHA
SCHEMBL21513960 0.74 GAA (0.70) GAAMAPTMEN1KMT2ATP53
SCHEMBL8026157 0.72 GAA (0.55) GAAEP300KAT2BKAT8IDO1
SCHEMBL592773 0.72 EP300 (0.51) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL29638 0.71 IDO1 (1.00) EP300KAT2BKAT8IDO1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230260787-A1 COMPOSITION FOR FORMING PROTECTIVE FILM AGAINST ALKALINE AQUEOUS HYDROGEN PEROXIDE, SUBSTRATE FOR PRODUCING SEMICONDUCTOR APPARATUS, METHOD FOR FORMING PROTECTIVE FILM, AND METHOD FOR FORMING PATTERN SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-17 US disclosed
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed