SCHEMBL7190237

SCHEMBL7190237

O=C(c1ccccc1O)C(Cl)Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
HPGD P15428 7/20 0.54
ALDH1A1 P00352 5/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
CA1 P00915 2/20 0.54
CA9 Q16790 2/20 0.54
CA12 O43570 1/20 0.54
CA2 P00918 1/20 0.54
HMGB1 P09429 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA7 P43166 1/20 0.54
NAPRT Q6XQN6 1/20 0.54
CA14 Q9ULX7 1/20 0.54
HSD17B10 Q99714 4/20 0.52
MAPT P10636 3/20 0.52
TSHR P16473 2/20 0.52
GAA P10253 2/20 0.48
MPO P05164 1/20 0.48
HIF1A Q16665 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3155318 0.79 KDM4E (0.56) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL12431221 0.77 CES2 (0.60) KDM4EHPGDALDH1A1TSHRMEN1
Salicylic Acid SCHEMBL28185563 0.77 ALDH1A1 (0.82) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL31276567 0.77 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL5415081 0.77 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL8445974 0.77 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL9861760 0.76 ALDH1A1 (0.59) HPGDALDH1A1SMN1; SMN2MAPTGAA
SCHEMBL28570713 0.76 HPGD (0.46) HPGDSMN1; SMN2HTTNPC1RAB9A
SCHEMBL2989477 0.76 KDM4E (0.52) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL3235570 0.74 KDM4E (0.50) KDM4EHPGDALDH1A1SMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240008958-A1 BIOGLASS FIBER REINFORCEMENT POLYMERS FOR ADDITIVE MANUFACTURING TU WIEN (AT) 2024-01-11 US disclosed
WO-2024010873-A1 BIOGLASS FIBER REINFORCEMENT OF ADDITIVELY MANUFACTURED POLYMERS ALIGN TECHNOLOGY, INC. (US) 2024-01-11 WO disclosed
EP-3946736-A1 SYSTEMS AND METHODS FOR METABOLIC ASSESSMENT UTILIZING 1-METHOXY-PMS Selux Diagnostics Inc. (US) 2022-02-09 EP disclosed
WO-2020198638-A1 SYSTEMS AND METHODS FOR METABOLIC ASSESSMENT UTILIZING 1-METHOXY-PMS SeLux Diagnostics, Inc. (US) 2020-10-01 WO disclosed
US-6613915-B1 Nickel (II) complexes of certain monoanionic bidentate ligands; pyrrole-2-imine ligand intermediate E. I. DU PONT DE NEMOURS AND COMPANY 2003-09-02 US disclosed
EP-0952997-A1 POLYMERIZATION OF OLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-03 EP disclosed
WO-1998030609-A1 POLYMERIZATION OF OLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-07-16 WO disclosed
US-4232032-A GROWTH PROMOTERS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-11-04 US disclosed