SCHEMBL8445974

SCHEMBL8445974

O=C(c1ccccc1O)C(Br)Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.54
HPGD P15428 6/20 0.54
ALDH1A1 P00352 4/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
CA1 P00915 2/20 0.54
CA9 Q16790 2/20 0.54
CA12 O43570 1/20 0.54
CA2 P00918 1/20 0.54
HMGB1 P09429 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA7 P43166 1/20 0.54
NAPRT Q6XQN6 1/20 0.54
CA14 Q9ULX7 1/20 0.54
HSD17B10 Q99714 4/20 0.52
TSHR P16473 2/20 0.52
MAPT P10636 2/20 0.52
GAA P10253 2/20 0.48
MPO P05164 1/20 0.48
HIF1A Q16665 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3235570 0.83 KDM4E (0.50) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL6542955 0.79 IDO1 (0.50) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL3155318 0.79 KDM4E (0.56) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL29758519 0.77 ELANE (0.46) HPGDALDH1A1SMN1; SMN2HSD17B10LMNA
SCHEMBL3365752 0.77 ELANE (0.46) HPGDALDH1A1SMN1; SMN2HSD17B10LMNA
SCHEMBL5415081 0.77 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL31276567 0.77 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL7190237 0.77 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA1
SCHEMBL235265 0.76 CES2 (0.58) HPGDALDH1A1TSHRMEN1KMT2A
SCHEMBL28629683 0.76 SLC6A2 (0.49) KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114771140-A Titanium dioxide-doped charcoal long-afterglow woodcarving and preparation method thereof 上饶昌浩玻璃有限公司 2022-07-22 CN claimed
CN-114656819-A Antifouling self-cleaning coating and preparation method thereof 江西昌浩实业有限公司 2022-06-24 CN claimed
CN-114771140-A Titanium dioxide-doped charcoal long-afterglow woodcarving and preparation method thereof 上饶昌浩玻璃有限公司 2022-07-22 CN disclosed
CN-114656819-A Antifouling self-cleaning coating and preparation method thereof 江西昌浩实业有限公司 2022-06-24 CN disclosed
CN-112194628-A Preparation method of nyconazole hydrochloride 扬子江药业集团广州海瑞药业有限公司 2021-01-08 CN disclosed
EP-0952997-A1 POLYMERIZATION OF OLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-03 EP disclosed
WO-1998030609-A1 POLYMERIZATION OF OLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-07-16 WO disclosed