SCHEMBL7190271

SCHEMBL7190271

Nc1cc(Br)cc(S(=O)(=O)c2ccc(N)c(Br)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.58
CA9 Q16790 9/20 0.58
CA1 P00915 8/20 0.58
CA12 O43570 7/20 0.58
CA4 P22748 6/20 0.58
CA14 Q9ULX7 6/20 0.58
CA6 P23280 5/20 0.58
CA5A P35218 5/20 0.58
CA7 P43166 5/20 0.58
CA5B Q9Y2D0 5/20 0.58
HTR6 P50406 5/20 0.47
PKM P14618 2/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 2/20 0.43
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
TSHR P16473 2/20 0.39
MPO P05164 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2811342 0.86 CA2 (0.76) CA2CA9CA1CA12CA4
SCHEMBL2810440 0.84 HTR6 (0.47) CA2CA9CA1CA12CA4
SCHEMBL7187819 0.82 HTR6 (0.69) CA2CA9CA1CA12CA4
SCHEMBL7192584 0.82 HTR6 (0.62) CA2CA9CA1CA12CA4
SCHEMBL7186604 0.81 LMNA (0.69) CA2CA9CA1CA12CA4
SCHEMBL7191069 0.79 LMNA (0.71) CA2CA9CA1CA12CA4
SCHEMBL11216559 0.77 CA1 (0.63) CA2CA9CA1CA12CA4
SCHEMBL878968 0.74 CA2 (1.00) CA2CA9CA1CA12CA4
SCHEMBL30351262 0.74 CA2 (1.00) CA2CA9CA1CA12CA4
SCHEMBL7190133 0.73 CA1 (0.58) CA2CA9CA1CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed