Gacyclidine

Gacyclidine

SCHEMBL7190367

C[C@H]1CCCC[C@]1(c1cccs1)N1CCCCC1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.57
PRCP P42785 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
SLC6A3 Q01959 1/20 0.42
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.40
CHRM3 P20309 2/20 0.39
OPRM1 P35372 1/20 0.39
OPRL1 P41146 1/20 0.39
SLC6A9 P48067 2/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gacyclidine SCHEMBL4465879 1.00 SIGMAR1 (0.57) SIGMAR1PRCPMEN1KMT2ASLC6A3
Gacyclidine SCHEMBL397836 1.00 SIGMAR1 (0.57) SIGMAR1PRCPMEN1KMT2ASLC6A3
Gacyclidine SCHEMBL3457748 1.00 SIGMAR1 (0.57) SIGMAR1PRCPMEN1KMT2ASLC6A3
Gacyclidine SCHEMBL5398234 0.99 SIGMAR1 (0.56) SIGMAR1PRCPMEN1KMT2ASLC6A3
Gacyclidine SCHEMBL1662223 0.99 SIGMAR1 (0.56) SIGMAR1PRCPMEN1KMT2ASLC6A3
SCHEMBL8206550 0.83 MEN1 (0.42) SIGMAR1PRCPMEN1KMT2ASLC6A3
Hydrochloric Acid SCHEMBL8205944 0.82 MEN1 (0.41) SIGMAR1PRCPMEN1KMT2ASLC6A3
SCHEMBL7700857 0.81 PRCP (0.51) SIGMAR1PRCPMEN1KMT2ASLC6A3
Gacyclidine SCHEMBL5402379 0.79 CYP1A2 (0.45) SIGMAR1PRCPMEN1KMT2ASLC6A3
Gacyclidine SCHEMBL14053284 0.78 GRIN1 (0.56) SIGMAR1PRCPMEN1KMT2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6524629-B1 20-30% of flavoneglycosides, 2.5-4.5% of ginkgolides A, B, C, and J, 2-4% of biloblaide, < 10% proanthocyanidines, < 10 ppm of an alkylphenol and ginkobiloba extract SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2003-02-25 US disclosed