Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8205944 | 0.99 | MEN1 (0.41) | MEN1PRCPKMT2ASIGMAR1OPRM1 | |
| SCHEMBL9142628 | 0.86 | MEN1 (0.41) | MEN1PRCPKMT2ASIGMAR1OPRM1 | |
| Gacyclidine SCHEMBL7190367 | 0.83 | SIGMAR1 (0.57) | MEN1PRCPKMT2ASIGMAR1OPRM1 | |
| Gacyclidine SCHEMBL397836 | 0.83 | SIGMAR1 (0.57) | MEN1PRCPKMT2ASIGMAR1OPRM1 | |
| Gacyclidine SCHEMBL3457748 | 0.83 | SIGMAR1 (0.57) | MEN1PRCPKMT2ASIGMAR1OPRM1 | |
| Gacyclidine SCHEMBL4465879 | 0.83 | SIGMAR1 (0.57) | MEN1PRCPKMT2ASIGMAR1OPRM1 | |
| Gacyclidine SCHEMBL5398234 | 0.82 | SIGMAR1 (0.56) | MEN1PRCPKMT2ASIGMAR1OPRM1 | |
| Gacyclidine SCHEMBL1662223 | 0.82 | SIGMAR1 (0.56) | MEN1PRCPKMT2ASIGMAR1OPRM1 | |
| SCHEMBL9143785 | 0.77 | MEN1 (0.65) | MEN1PRCPKMT2ASIGMAR1 | |
| SCHEMBL9143818 | 0.77 | MEN1 (0.47) | MEN1PRCPKMT2ASIGMAR1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107495-A | REACTING SPECIFIED 1-(2- OR 3-THIENYL) CYCLOHEXANES WITH A 1,5-DIHALOPENTANE TO FORM CYCLIC (THIENYLCYCLOHEXYL)AMINES SUCH AS 2-ALKYL-(3-THIENYL)CYCLOHEXYL PIPERIDINE; USE AS INTERMEDIATES TO RADIOACTIVE LABELLED MOLECULES | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 2000-08-22 | — | — | US | disclosed |