Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652185 | 0.82 | SMN1; SMN2 (0.74) | DHPSRAB9AGAAMAPTNPSR1 | |
| SCHEMBL27758303 | 0.81 | PTGS1 (0.57) | DHPSRAB9AGAAMAPTNPSR1 | |
| SCHEMBL7183238 | 0.81 | RAB9A (0.67) | RAB9AGAAMAPTSMN1; SMN2TP53 | |
| SCHEMBL7300718 | 0.81 | SMO (0.69) | DHPSRAB9AGAAMAPTNPSR1 | |
| SCHEMBL21652187 | 0.81 | MEN1 (0.68) | DHPSRAB9AHDAC8HDAC6HDAC3 | |
| SCHEMBL3822225 | 0.81 | PTGS1 (0.73) | DHPSRAB9AGAANPSR1HDAC8 | |
| SCHEMBL1496348 | 0.81 | CA12 (0.58) | DHPSRAB9AHDAC8HDAC6HDAC3 | |
| SCHEMBL1548766 | 0.80 | PTGS1 (0.56) | DHPSRAB9AGAAMAPTNPSR1 | |
| SCHEMBL9284694 | 0.80 | CFTR (0.63) | DHPSRAB9ANPSR1HDAC8HDAC6 | |
| SCHEMBL8376765 | 0.80 | CA1 (0.59) | DHPSRAB9AGAAMAPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366116-A2 | POLYPROPYLENE RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002046300-A2 | POLYPROPYLENE RESIN COMPOSITIONS | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2002-06-13 | — | — | WO | disclosed |