Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.67 |
| ▸ | NPC1 | O15118 | 8/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.67 |
| ▸ | RELA | Q04206 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | PNLIP | P16233 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058035 | 0.86 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL10880537 | 0.82 | TDP1 (0.58) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL7188679 | 0.82 | ALDH1A1 (0.68) | RAB9ANPC1LMNATP53HTT | |
| SCHEMBL7181742 | 0.82 | MEN1 (0.71) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL14688750 | 0.82 | NPC1 (0.63) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL3684485 | 0.81 | HPGD (0.79) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL20413311 | 0.81 | NPC1 (0.67) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL29519361 | 0.81 | HPGD (0.79) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL7190812 | 0.81 | DHPS (0.62) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL5079177 | 0.80 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366116-A2 | POLYPROPYLENE RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002046300-A2 | POLYPROPYLENE RESIN COMPOSITIONS | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2002-06-13 | — | — | WO | disclosed |