Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.69 |
| ▸ | RORC | P51449 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | TYK2 | P29597 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687877 | 0.96 | SMO (0.73) | SMORORCRAB9AMAPTGAA | |
| SCHEMBL11133130 | 0.88 | TDP1 (0.63) | SMORORCRAB9AMAPTGAA | |
| SCHEMBL21588735 | 0.85 | ALDH1A1 (0.65) | SMORAB9AGAANPSR1NPC1 | |
| SCHEMBL5369677 | 0.84 | RORC (0.76) | SMORORCRAB9AMAPTNPC1 | |
| SCHEMBL21652185 | 0.83 | SMN1; SMN2 (0.74) | RAB9AMAPTGAANPSR1NPC1 | |
| SCHEMBL31078118 | 0.82 | SMO (1.00) | SMORORCRAB9AMAPTNPC1 | |
| SCHEMBL8055108 | 0.82 | SMO (0.71) | SMORORCRAB9AMAPTNPC1 | |
| SCHEMBL31078128 | 0.82 | RORC (0.77) | SMORORCRAB9AMAPTNPC1 | |
| SCHEMBL2117583 | 0.82 | SMO (0.75) | SMORORCRAB9AMAPTNPC1 | |
| SCHEMBL1203522 | 0.81 | SMO (0.80) | SMORAB9AMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245633-A1 | ROR Gamma Agonists as Enhancers of Protective Immunity | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-07-25 | — | — | US | disclosed |
| WO-2017079120-A1 | ROR GAMMA AGONISTS AS ENHANCERS OF PROTECTIVE IMMUNITY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-05-11 | — | — | WO | disclosed |
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245633-A1 | ROR Gamma Agonists as Enhancers of Protective Immunity | RORC, RORB, RORA | SMO 1935/4885RORC 1/4885RAB9A 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.