SCHEMBL7192533

SCHEMBL7192533

Nc1cc(C(F)(F)F)cc(S(=O)(=O)c2ccc(N)c(C(F)(F)F)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 11/20 0.44
FFAR1 O14842 3/20 0.44
ALDH1A1 P00352 2/20 0.42
HTR6 P50406 2/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 2/20 0.39
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 2/20 0.35
MPO P05164 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
MAPK1 P28482 1/20 0.35
KIF11 P52732 1/20 0.35
HSP90AA1 P07900 1/20 0.34
CXCR5 P32302 1/20 0.34
APLNR P35414 1/20 0.34
CCR6 P51684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2810971 0.86 FFAR4 (0.54) FFAR4FFAR1ALDH1A1HTR6PKM
SCHEMBL2810521 0.84 LMNA (0.42) ALDH1A1HTR6PKMLMNAGAA
SCHEMBL7195572 0.83 HTR6 (0.55) ALDH1A1HTR6PKMLMNATSHR
SCHEMBL7199024 0.83 HTR6 (0.62) FFAR4FFAR1ALDH1A1HTR6PKM
SCHEMBL7195357 0.82 LMNA (0.62) FFAR4FFAR1ALDH1A1HTR6PKM
SCHEMBL7189582 0.80 LMNA (0.65) ALDH1A1LMNAMAPTTSHRMAPK1
SCHEMBL7181916 0.77 TSHR (0.42) FFAR4FFAR1ALDH1A1HTR6PKM
SCHEMBL10389017 0.75 FFAR4 (0.49) FFAR4FFAR1LMNA
SCHEMBL7187838 0.75 FFAR4 (0.45) FFAR4FFAR1ALDH1A1HTR6PKM
SCHEMBL11685070 0.74 CA12 (0.58) FFAR4FFAR1PKMGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed