SCHEMBL7192589

SCHEMBL7192589

Cc1cc(C(=O)c2ccc(N)cc2C)ccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.50
NPC1 O15118 2/20 0.50
MITF O75030 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 7/20 0.47
HTT P42858 2/20 0.47
MAPK1 P28482 2/20 0.47
MAPK13 O15264 2/20 0.47
MAPK12 P53778 2/20 0.47
MAPK11 Q15759 2/20 0.47
MAPK14 Q16539 2/20 0.47
ALDH1A1 P00352 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
THRB P10828 1/20 0.42
PKM P14618 1/20 0.42
APEX1 P27695 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31457279 0.85 NPC1 (0.47) POLBNPC1MITFLMNAMAPT
SCHEMBL7189766 0.85 NPC1 (0.47) POLBNPC1MITFLMNAMAPT
SCHEMBL7195606 0.84 LMNA (0.54) POLBNPC1MITFLMNAMAPT
SCHEMBL7186665 0.83 ALDH1A1 (0.52) POLBNPC1MITFLMNAMAPT
SCHEMBL436565 0.83 LMNA (0.56) POLBNPC1MITFLMNAMAPT
SCHEMBL6651159 0.83 MAPK13 (0.65) POLBNPC1MITFLMNAMAPT
SCHEMBL7194269 0.83 POLB (0.68) POLBNPC1MITFLMNAMAPT
SCHEMBL10625343 0.81 MAPT (0.55) POLBNPC1MITFLMNAMAPT
SCHEMBL7194336 0.79 NPC1 (0.78) POLBNPC1MITFLMNAMAPT
SCHEMBL7189805 0.78 NPC1 (0.45) POLBNPC1MITFLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286359-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2022-03-29 US disclosed
US-11111345-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2021-09-07 US disclosed
US-20170327657-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2017-11-16 US disclosed
US-9765194-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2017-09-19 US disclosed
EP-2878617-B1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2017-03-01 EP disclosed
US-20150210813-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2015-07-30 US disclosed
EP-2878617-A1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2015-06-03 EP disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed