SCHEMBL719442

SCHEMBL719442

CC1CCOC(=O)c2ccc(cc2)C(=O)OC1

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.31
TSHR P16473 1/20 0.31
GRM2 Q14416 1/20 0.30
TP53 P04637 1/20 0.30
PKM P14618 1/20 0.30
PPARG P37231 1/20 0.30
NCOA2 Q15596 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23855448 0.90 HRH3 (0.33) MAPK1TSHRALDH1A1HPGD
SCHEMBL30084350 0.87 MEN1 (0.31)
SCHEMBL28411162 0.86 KMT2A (0.32)
SCHEMBL11146243 0.86 NSD2 (0.32) MAPK1GRM2PKMALDH1A1HPGD
SCHEMBL3179787 0.83 CLK1 (0.30)
SCHEMBL7783365 0.78 NPC1 (0.33) ALDH1A1
SCHEMBL30874264 0.77 ALDH1A1 (0.36) MAPK1TSHRGRM2ALDH1A1HPGD
SCHEMBL29241897 0.77
SCHEMBL2477501 0.77 CA1 (0.38) GRM2HPGD
SCHEMBL2885573 0.76 MEN1 (0.33) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1718719-A1 MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH IMPROVED PERFUME The Procter and Gamble Company (US) 2006-11-08 EP claimed
WO-2005085404-A1 MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH IMPROVED PERFUME THE PROCTER & GAMBLE COMPANY (US) 2005-09-15 WO claimed
EP-0009950-B1 BLOCK COPOLYMER HOT MELT ADHESIVE COMPOSITION AND METHOD OF FILLING A CAVITY MONSANTO COMPANY (US) 1984-04-18 EP claimed
EP-0009949-B1 BLOCK COPOLYMER HOT MELT ADHESIVE COMPOSITIONS, A METHOD OF FILLING A CAVITY IN A SUBSTRATE THEREWITH, AND A SUBSTRATE WITH A CAVITY FILLED WITH SUCH A COMPOSITION MONSANTO COMPANY (US) 1984-03-21 EP claimed
EP-0009951-B1 A HOT MELT ADHESIVE COMPOSITION AND A PROCESS FOR FILLING A CAVITY IN A SUBSTRATE WITH THIS COMPOSITION MONSANTO COMPANY (US) 1984-03-21 EP claimed
EP-2552996-B1 ORGANOSILICONES PROCTER & GAMBLE (US) 2019-05-22 EP disclosed
EP-2552400-B1 COMPOSITION COMPRISING MODIFIED ORGANOSILICONES PROCTER & GAMBLE (US) 2018-02-21 EP disclosed
US-20170183452-A1 ORGANOSILICONES PROCTER & GAMBLE (US) 2017-06-29 US disclosed
US-9650593-B2 Organosilicones THE PROCTER & GAMBLE COMPANY (US) 2017-05-16 US disclosed
US-20160060581-A1 ORGANOSILICONES PROCTER & GAMBLE (US) 2016-03-03 US disclosed
US-9212338-B2 Organosilicones THE PROCTER & GAMBLE COMPANY (US) 2015-12-15 US disclosed
US-20150093350-A1 ORGANOSILICONES PROCTER & GAMBLE (US) 2015-04-02 US disclosed
EP-1718719-A1 MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH IMPROVED PERFUME The Procter and Gamble Company (US) 2006-11-08 EP disclosed
WO-2005085404-A1 MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH IMPROVED PERFUME THE PROCTER & GAMBLE COMPANY (US) 2005-09-15 WO disclosed
WO-2005085409-A1 MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH BLOOMING PERFUME THE PROCTER & GAMBLE COMPANY (US) 2005-09-15 WO disclosed
US-20050192207-A1 Multiple use fabric conditioning composition with blooming perfume PROCTER & GAMBLE COMPANY, THE 2005-09-01 US disclosed
US-20050192204-A1 Multiple use fabric conditioning composition with improved perfume PROCTER & GAMBLE COMPANY, THE 2005-09-01 US disclosed
EP-0009951-B1 A HOT MELT ADHESIVE COMPOSITION AND A PROCESS FOR FILLING A CAVITY IN A SUBSTRATE WITH THIS COMPOSITION MONSANTO COMPANY (US) 1984-03-21 EP disclosed
US-4103726-A Method of making a tire and said tire THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-08-01 US disclosed
US-4097548-A COPOLYMER OF ETHYLENE AND ETHYL ACRYLATE OR METHACRYLATE, COPOLYESTERS OF TEREPHTHALIC ACID, ETHYLENE GLYCOL NEOPENTYL GLYCOL, ISOPHTHALIC ACID AND AZELAIC ACID THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150093350-A1 ORGANOSILICONES NISCH, XRCC6, RAD50 MAPK1 3987/4885TSHR 4805/4885GRM2 4479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.