Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2429129 | 0.90 | ITGB1 (0.55) | RAB9AKMT2AMAPTPOLBITGB1 | |
| SCHEMBL72718 | 0.89 | MAPT (0.57) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL14505040 | 0.88 | MAPT (0.45) | RAB9AMEN1NPC1KMT2AMAPT | |
| SCHEMBL70951 | 0.87 | RAB9A (0.52) | RAB9AMEN1NPC1KMT2AMAPT | |
| SCHEMBL14591763 | 0.84 | RAB9A (0.49) | RAB9AMEN1NPC1KMT2AMAPT | |
| SCHEMBL91593 | 0.83 | RAB9A (0.52) | RAB9AMEN1NPC1KMT2AMAPT | |
| SCHEMBL92383 | 0.81 | RAB9A (0.60) | RAB9AMEN1NPC1KMT2AMAPT | |
| SCHEMBL2432469 | 0.80 | ALDH1A1 (0.44) | RAB9AMEN1NPC1KMT2AMAPT | |
| SCHEMBL3579447 | 0.80 | ITGB1 (0.56) | RAB9AMEN1NPC1KMT2AMAPT | |
| SCHEMBL72352 | 0.76 | POLB (0.61) | MEN1KMT2AMAPTPOLBITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961750-B1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO CO LTD (JP) | 2013-09-18 | — | — | EP | disclosed |