Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71948 | 0.89 | RAB9A (0.48) | MAPTPOLBMEN1KMT2AITGB1 | |
| SCHEMBL14626962 | 0.88 | POLB (0.63) | MAPTPOLBMEN1KMT2AS1PR2 | |
| SCHEMBL72352 | 0.88 | POLB (0.61) | MAPTPOLBMEN1KMT2AS1PR2 | |
| SCHEMBL2429129 | 0.87 | ITGB1 (0.55) | MAPTPOLBKMT2AITGB1ITGA4 | |
| SCHEMBL14505040 | 0.86 | MAPT (0.45) | MAPTPOLBMEN1KMT2AITGB1 | |
| SCHEMBL14591773 | 0.85 | POLB (0.58) | MAPTPOLBMEN1KMT2AS1PR2 | |
| SCHEMBL92336 | 0.83 | MEN1 (0.55) | MAPTPOLBMEN1KMT2AS1PR2 | |
| SCHEMBL2432469 | 0.80 | ALDH1A1 (0.44) | MAPTMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL3579447 | 0.78 | ITGB1 (0.56) | MAPTMEN1KMT2AS1PR2ITGB1 | |
| SCHEMBL70951 | 0.77 | RAB9A (0.52) | MAPTPOLBMEN1KMT2AITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961750-B1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO CO LTD (JP) | 2013-09-18 | — | — | EP | disclosed |