Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923510 | 0.81 | POLB (0.49) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6923507 | 0.81 | POLB (0.49) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13878064 | 0.79 | HSD11B1 (0.41) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23417534 | 0.79 | HSD11B1 (0.41) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23417537 | 0.79 | HSD11B1 (0.41) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28988279 | 0.78 | MGLL (0.43) | CYP1A2FAAHMGLL | |
| SCHEMBL6921473 | 0.76 | ANPEP (0.45) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6924631 | 0.76 | ANPEP (0.45) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6924635 | 0.76 | ANPEP (0.45) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25276584 | 0.73 | HSD11B1 (0.57) | HSD11B1ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150414-B2 | Nanocomposite and dispersion comprising the same | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20120053288-A1 | NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2012-03-01 | — | — | US | disclosed |