SCHEMBL7195382

SCHEMBL7195382

CC(C)CCCCC(Cl)(Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27542726 0.97 LMNA (0.43) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL28491816 0.92 LMNA (0.41) LMNAMEN1CYP3A4ALOX15KMT2A
Hydrochloric Acid SCHEMBL11314074 0.87 OPRM1 (0.38) LMNA
SCHEMBL29167384 0.81 LMNA (0.43) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL384245 0.79
SCHEMBL21651579 0.77 LMNA (0.40) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL7499532 0.77 ACACB (0.36)
SCHEMBL11048189 0.74
SCHEMBL108076 0.74 LMNA (0.71) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL18720922 0.74 LMNA (0.48) LMNAMEN1CYP3A4ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908469-B1 Olefin polymerization catalyst precursor UNION CARBIDE CHEM PLASTIC (US) 2003-05-02 EP disclosed
EP-0908470-B1 Olefin polymerization catalyst precursor UNION CARBIDE CHEM PLASTIC (US) 2002-11-20 EP disclosed
EP-0908471-B1 Olefin polymerization catalyst precursor UNION CARBIDE CHEM PLASTIC (US) 2002-07-24 EP disclosed
EP-0908472-B1 Olefin polymerization catalyst precursor UNION CARBIDE CHEM PLASTIC (US) 2002-07-17 EP disclosed
EP-0481749-B1 Olefin polymerization catalyst UNION CARBIDE CHEM PLASTIC (US) 1999-07-21 EP disclosed
EP-0908470-A2 Olefin polymerization catalyst precursor UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-04-14 EP disclosed
EP-0908472-A2 Olefin polymerization catalyst precursor UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-04-14 EP disclosed
EP-0908469-A2 Olefin polymerization catalyst precursor UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-04-14 EP disclosed
EP-0908471-A2 Olefin polymerization catalyst precursor UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-04-14 EP disclosed
US-5141910-A Magnesium titanium complex alkoxide catalyst precursor SHELL OIL COMPANY (US) 1992-08-25 US disclosed
EP-0481749-A2 Olefin polymerization catalyst SHELL OIL COMPANY (US) 1992-04-22 EP disclosed
US-5082907-A Coordination catalysts SHELL OIL COMPANY (US) 1992-01-21 US disclosed