Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196017 | 0.94 | SMN1; SMN2 (0.39) | POLBRXFP1NLRP3KMT2AMAPT | |
| SCHEMBL6833113 | 0.83 | SMN1; SMN2 (0.46) | POLBRXFP1NLRP3KMT2AMAPT | |
| SCHEMBL6834350 | 0.76 | ALDH1A1 (0.50) | POLBNLRP3KMT2AMAPTMEN1 | |
| SCHEMBL6713494 | 0.74 | POLB (0.39) | POLBRXFP1NLRP3KMT2AMAPT | |
| SCHEMBL6834072 | 0.74 | ALDH1A1 (0.41) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL6834504 | 0.73 | LMNA (0.47) | RXFP1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6707690 | 0.73 | POLB (0.38) | POLBRXFP1NLRP3KMT2AMAPT | |
| SCHEMBL6830705 | 0.73 | ALB (0.42) | POLBRXFP1KMT2A | |
| SCHEMBL6833683 | 0.73 | NR1H4 (0.48) | NLRP3CACNA1H | |
| SCHEMBL6835671 | 0.72 | LMNA (0.39) | POLBRXFP1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |