Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196015 | 0.94 | POLB (0.37) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6833113 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6834350 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AMEN1POLBNLRP3 | |
| SCHEMBL6834072 | 0.80 | ALDH1A1 (0.41) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6834504 | 0.80 | LMNA (0.47) | SMN1; SMN2KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL6830705 | 0.79 | ALB (0.42) | KMT2ARXFP1POLB | |
| SCHEMBL6833683 | 0.79 | NR1H4 (0.48) | NLRP3ALDH1A1 | |
| SCHEMBL6835671 | 0.79 | LMNA (0.39) | RXFP1POLBPKMLMNATP53 | |
| SCHEMBL6834079 | 0.79 | NHERF1 (0.44) | KMT2AMEN1ALDH1A1KDM4EAKR1C2 | |
| SCHEMBL6833766 | 0.79 | PARP14 (0.43) | KMT2AMEN1ALDH1A1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |