Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29510856 | 1.00 | HTT (0.50) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1027272 | 0.88 | HTT (0.50) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1027274 | 0.85 | HTT (0.48) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL29613147 | 0.83 | HTT (0.53) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL263618 | 0.83 | HTT (0.53) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL7768580 | 0.82 | HTT (0.51) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL17333428 | 0.82 | HTT (0.51) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1027134 | 0.81 | HTT (0.48) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL723710 | 0.81 | HTR1B (0.44) | HTTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11791487 | 0.80 | LMNA (0.51) | HTTALDH1A1KDM4EHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637441-B2 | Prodrugs of the tyrosine kinase inhibitor for treating cancer | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2026-05-26 | — | — | US | disclosed |
| EP-4647434-A1 | MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 | Unicet Biotech Co., LLC (CN) | 2025-11-12 | — | — | EP | disclosed |
| EP-3684374-B1 | 4'-FLUORO-2'-METHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | RIBOSCIENCE LLC (US) | 2025-07-30 | — | — | EP | disclosed |
| US-12110308-B2 | Phosphor(n)amidatacetal and phosph(on)atalcetal compounds | NUCORION PHARMACEUTICALS, INC. (US) | 2024-10-08 | — | — | US | disclosed |
| WO-2024146627-A1 | MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 | 北京清辉联诺生物科技有限责任公司 | 2024-07-11 | — | — | WO | disclosed |
| US-20240116972-A1 | 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS | SOUTHERN RES INST (US) | 2024-04-11 | — | — | US | disclosed |
| EP-4335496-A2 | PHOSPHOR(N)AMIDATACETAL AND PHOSPH(ON)ATALCETAL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. (US) | 2024-03-13 | — | — | EP | disclosed |
| US-11925658-B2 | Phosphoramidate derivatives of 5-fluoro-2′—deoxyuridine for use in the treatment of cancer | NuCana plc (GB) | 2024-03-12 | — | — | US | disclosed |
| CN-117402189-A | Phosphoramidate (phosphonate) acetals and phospho (phosphonate) acetal compounds | 广东集宝医药技术有限公司 | 2024-01-16 | — | — | CN | disclosed |
| US-11858956-B2 | 6-aza-nucleoside prodrugs as antiviral agents for treating virus infections | SOUTHERN RESEARCH INSTITUTE (US) | 2024-01-02 | — | — | US | disclosed |
| US-7235686-B2 | Process for preparing phosphoric esters | DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-06-26 | — | — | US | disclosed |
| EP-1403272-B1 | PROCESS FOR PREPARATION OF PHOSPHORIC ESTERS | DAIHACHI CHEM IND (JP) | 2006-05-24 | — | — | EP | disclosed |
| US-20040254390-A1 | Process for preparing phosphoric esters | DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1403272-A1 | PROCESS FOR PREPARATION OF PHOSPHORIC ESTERS | DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-5011964-A | Phospholipase cleavage of water-insoluble ester yields chromogen for colorimetric analysis | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-04-30 | — | — | US | disclosed |
| US-4144394-A | FLAME RETARDANTS FOR POLYMERS | MONSANTO COMPANY (US) | 1979-03-13 | — | — | US | disclosed |
| US-4124400-A | Flame retardant polymer compositions | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4086302-A | FLAME RETARDANTS | MONSANTO COMPANY (US) | 1978-04-25 | — | — | US | disclosed |
| US-4062909-A | FIRE RETARDANTS | MONSANTO COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-3965220-A | AMINE CATALYST | MONSANTO COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12110308-B2 | Phosphor(n)amidatacetal and phosph(on)atalcetal compounds | PYGL, MTMR1, PTEN | HTT 4275/4885ALDH1A1 3472/4885KDM4E 2892/4885 |
| US-12637441-B2 | Prodrugs of the tyrosine kinase inhibitor for treating cancer | EGFR, ERBB2, MET | HTT 4598/4885ALDH1A1 3172/4885KDM4E 1084/4885 |
| US-20240116972-A1 | 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS | MTAP, GALE, TPMT | HTT 2009/4885ALDH1A1 1623/4885KDM4E 184/4885 |
| US-20040254390-A1 | Process for preparing phosphoric esters | PHOSPHO1, INPPL1, CYP4A11 | HTT 3207/4885ALDH1A1 2021/4885KDM4E 3338/4885 |
| US-11925658-B2 | Phosphoramidate derivatives of 5-fluoro-2′—deoxyuridine for use in the treatment of cancer | SLC29A2, SLC29A1, TYMP | HTT 3959/4885ALDH1A1 2432/4885KDM4E 3294/4885 |
| US-11858956-B2 | 6-aza-nucleoside prodrugs as antiviral agents for treating virus infections | MTAP, GALE, TPMT | HTT 2009/4885ALDH1A1 1623/4885KDM4E 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.