Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | EPM2A | O95278 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230 | 0.85 | CYP2A6 (0.73) | CYP2A6DYRK1ACDK9CA2CA12 | |
| SCHEMBL3789969 | 0.83 | CYP2A6 (0.71) | CYP2A6KDM4EHSD17B10CYP3A4CYP2D6 | |
| SCHEMBL29951028 | 0.83 | CYP2A6 (0.71) | CYP2A6KDM4EHSD17B10CYP3A4CYP2D6 | |
| SCHEMBL9754623 | 0.79 | CYP2A6 (0.65) | CYP2A6DYRK1ACDK9CTNNB1WNT3A | |
| SCHEMBL8052991 | 0.79 | CYP2A6 (0.66) | CYP2A6DYRK1ACDK9EPM2APTPRC | |
| SCHEMBL6599379 | 0.79 | CYP2A6 (0.66) | CYP2A6DYRK1ACDK9EPM2APTPRC | |
| SCHEMBL5029999 | 0.79 | CYP2A6 (0.66) | CYP2A6DYRK1ACDK9EPM2APTPRC | |
| SCHEMBL7367499 | 0.77 | CYP2A6 (0.62) | CYP2A6DYRK1ACDK9CTNNB1WNT3A | |
| SCHEMBL15676441 | 0.76 | CYP2A6 (0.61) | CYP2A6DYRK1ACDK9CTNNB1WNT3A | |
| SCHEMBL17821821 | 0.76 | CYP2A6 (0.61) | CYP2A6DYRK1ACDK9EPM2APTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606823-A | Method for converting aromatic aldehyde into aromatic nitrile by using inorganic ammonium as nitrogen source and promoted by sulfur powder | 湘潭大学 | 2020-09-01 | — | — | CN | claimed |
| CN-107266413-A | Heterocycle and phenylpropionic acid derivative and its preparation method and application | 上海大学 | 2017-10-20 | — | — | CN | claimed |
| CN-106459062-A | Substituted [1,2,4] triazolo [1,5-a ] pyrimidin-7-yl compounds as PDE2 inhibitors | 达特神经科学(开曼)有限公司 | 2017-02-22 | — | — | CN | claimed |
| EP-4727940-A1 | DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF | Linkcure Therapeutics (KY) | 2026-04-22 | — | — | EP | disclosed |
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| US-12378231-B2 | Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof | APOGEE PHARMACEUTICALS, INC. (CA) | 2025-08-05 | — | — | US | disclosed |
| CN-120192307-A | Compounds targeting p53 mutations | 上海齐鲁制药研究中心有限公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2025124698-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-19 | — | — | WO | disclosed |
| EP-3528813-B1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ABS DEV 1 INC (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119735563-A | Thiazolidinones as NLRP3 protein inhibitors | 润药仁智(北京)科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119666797-A | Method for rapidly evaluating sperm motility and sperm quality in multi-dimension manner | 中国药科大学 | 2025-03-21 | — | — | CN | disclosed |
| US-4372970-A | NONPHYTOTOXIC, PHOTOSTABLE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1983-02-08 | — | — | US | disclosed |
| US-4371607-A | 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-01 | — | — | US | disclosed |
| EP-0041675-A2 | 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-16 | — | — | EP | disclosed |
| WO-1981001408-A1 | SUBSTITUTED ACETIC ACID ESTERS AS PESTICIDES | SOREX LTD (GB) | 1981-05-28 | — | — | WO | disclosed |
| EP-0029360-A1 | Pesticidal compounds, compositions containing them and methods of killing arthropods using them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-05-27 | — | — | EP | disclosed |
| US-4259338-A | Benzofuranyl-tetrahydropyridines and -piperidines, their acid addition salts and antidepressant preparations thereof | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4255423-A | BACTERICIDES | MERCK & CO., INC. (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0006524-A1 | Tetrahydropyridine and tetrahydropiperidine derivatives, their acid addition salts, processes for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| US-4017313-A | Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378231-B2 | Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof | MGLL, PNLIP, LPL | CYP2A6 822/4885DYRK1A 3319/4885CDK9 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.