Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 1/20 | 0.84 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.84 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CDC25A | P30304 | 1/20 | 0.59 |
| ▸ | CDC25C | P30307 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196601 | 1.00 | GABRA3 (0.84) | GABRA3GABRA2GABRB2MAPTNPC1 | |
| SCHEMBL1576913 | 0.89 | MAPT (0.75) | GABRA3GABRA2GABRB2MAPTNPC1 | |
| SCHEMBL1576914 | 0.89 | MAPT (0.75) | GABRA3GABRA2GABRB2MAPTNPC1 | |
| SCHEMBL7180833 | 0.86 | ABCG2 (0.86) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7180829 | 0.86 | ABCG2 (0.86) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10321326 | 0.83 | GABRA3 (0.70) | GABRA3GABRA2GABRB2MAPTALDH1A1 | |
| SCHEMBL10321325 | 0.83 | GABRA3 (0.70) | GABRA3GABRA2GABRB2MAPTALDH1A1 | |
| SCHEMBL31501090 | 0.83 | GABRA3 (0.70) | GABRA3GABRA2GABRB2MAPTALDH1A1 | |
| SCHEMBL10384464 | 0.83 | GABRA3 (0.84) | GABRA3GABRA2GABRB2MAPTALDH1A1 | |
| SCHEMBL7188106 | 0.83 | MAPT (1.00) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | claimed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | claimed |
| US-11485722-B2 | Cyclopenta[c]chromium compound and preparation method therefor | SOOCHOW UNIVERSITY (CN) | 2022-11-01 | — | — | US | disclosed |
| CN-108774207-B | Cyclopenta [ c ] chromene compounds and process for preparing the same | 苏州大学张家港工业技术研究院 | 2021-12-17 | — | — | CN | disclosed |
| US-20210147376-A1 | CYCLOPENTA[C]CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR | SOOCHOW UNIVERSITY (CN) | 2021-05-20 | — | — | US | disclosed |
| WO-2020024099-A1 | CYCLOPENTADIENYL [C] CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR | 苏州大学张家港工业技术研究院 | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147376-A1 | CYCLOPENTA[C]CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR | CDYL, LAS1L, YAP1 | GABRA3 3852/4885GABRA2 4025/4885GABRB2 4342/4885 |
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | GABRA3 1792/4885GABRA2 2011/4885GABRB2 1459/4885 |
| US-11485722-B2 | Cyclopenta[c]chromium compound and preparation method therefor | CDYL, LAS1L, YAP1 | GABRA3 3852/4885GABRA2 4025/4885GABRB2 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.