SCHEMBL719673

SCHEMBL719673

C=C(C)C(=O)OCCCCCOC(=O)CCP(=O)(O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
THRB P10828 1/20 0.41
HTR2C P28335 1/20 0.36
NAAA Q02083 1/20 0.36
DGKA P23743 1/20 0.36
ALDH1A1 P00352 1/20 0.36
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PLA2G2A P14555 2/20 0.34
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
P2RY10 O00398 2/20 0.33
GPR34 Q9UPC5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1173876 1.00 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL23064056 1.00 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3446714 1.00 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL722552 1.00 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL717824 1.00 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL720774 0.98 TSHR (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22878827 0.91 TSHR (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL13109395 0.88 TSHR (0.51) TSHRPOLBAPEX1HTTTDP1
SCHEMBL2943884 0.87 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15389725 0.87 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984673-B2 Dental cement composition KURARAY CO., LTD. (JP) 2006-01-10 US claimed
JP-3294286-A None JP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
EP-3880156-B1 STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-08-20 EP disclosed
EP-4175584-B1 PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-07-30 EP disclosed
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-10-31 US disclosed
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-08-27 US disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-20240189195-A1 DENTAL POLYMERIZABLE COMPOSITION GC CORPORATION (JP) 2024-06-13 US disclosed
CN-110302062-B Dental adhesive glass ion water-gate composition with good removability 株式会社松风 2024-06-07 CN disclosed
EP-1285947-A1 ANTIMICROBIAL COMPOSITION KURARAY CO., LTD. (JP) 2003-02-26 EP disclosed
EP-1269968-A1 Dental cement composition KURARAY CO., LTD. (JP) 2003-01-02 EP disclosed
EP-1269967-A1 Dental composition kit KURARAY CO., LTD. (JP) 2003-01-02 EP disclosed
US-20020198284-A1 Adhesive composition KURARAY CO. LTD, (JP) 2002-12-26 US disclosed
EP-1262530-A1 ADHESIVE COMPOSITION KURARAY CO., LTD. (JP) 2002-12-04 EP disclosed
US-6458868-B1 Organophosphorus compounds for dental polymerizable compositions KURARAY CO., LTD. (JP) 2002-10-01 US disclosed
CN-1310720-A Organophosphorus compounds for dental polymerizable compositions KURARAY CO (JP) 2001-08-29 CN disclosed
EP-1084131-A1 ORGANOPHOSPHORUS COMPOUNDS FOR DENTAL POLYMERIZABLE COMPOSITIONS KURARAY CO., LTD. (JP) 2001-03-21 EP disclosed
WO-2000058316-A1 ORGANOPHOSPHORUS COMPOUNDS FOR DENTAL POLYMERIZABLE COMPOSITIONS KURARAY CO., LTD. (JP) 2000-10-05 WO disclosed
JP-H03294286-A (METH)ACRYLIC ACID ESTER DERIVATIVE SHIYOUFUU:KK 1991-12-25 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials CDH1, F12, ACTN1 TSHR 4762/4885POLB 279/4885APEX1 85/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 TSHR 3141/4885POLB 1067/4885APEX1 65/4885
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials CDH1, F12, ACTN1 TSHR 4762/4885POLB 279/4885APEX1 85/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.