Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087234 | 0.94 | — | — | |
| SCHEMBL119092 | 0.93 | KMT2A (0.35) | ALDH1A1HSD17B10TSHRMAPTKDM4E | |
| SCHEMBL10087230 | 0.91 | GAA (0.33) | ALDH1A1HSD17B10MAPTKDM4ELMNA | |
| SCHEMBL10087235 | 0.90 | — | — | |
| SCHEMBL10087231 | 0.89 | LMNA (0.36) | ALDH1A1HSD17B10TSHRMAPTKDM4E | |
| SCHEMBL719376 | 0.89 | KDM4E (0.34) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL119041 | 0.89 | KDM4E (0.33) | ALDH1A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL719772 | 0.88 | MAPT (0.31) | MAPT | |
| SCHEMBL719670 | 0.88 | L3MBTL1 (0.31) | — | |
| SCHEMBL718324 | 0.88 | MAPT (0.38) | ALDH1A1MAPTKDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | DPYD, DHODH, TYMP | ALDH1A1 1043/4885HSD17B10 2183/4885TSHR 1099/4885 |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | TYMS, DHFR, UNG | ALDH1A1 3537/4885HSD17B10 3547/4885TSHR 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.