Iodide

Iodide

SCHEMBL7197154

Cc1ccc([P+](CCCO)(c2ccc(C)cc2)c2ccc(C)cc2)cc1.[I-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 2/20 0.33
HIF1A Q16665 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.32
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
CHRNA7 P36544 2/20 0.31
LMNA P02545 1/20 0.31
SLC6A4 P31645 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TRAP1 Q12931 1/20 0.30
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7194031 0.96 HIF1A (0.34) HIF1AACHETDP1GAATSHR
Bromide SCHEMBL7194017 0.96 HIF1A (0.34) HIF1AACHETDP1GAATSHR
Phosphoric Acid SCHEMBL7199855 0.89 GAA (0.40) GAATSHRALDH1A1CYP2C19LMNA
Acetic Acid SCHEMBL8750056 0.87 STAT3 (0.35) TDP1TSHRALDH1A1CYP1A2CYP2D6
Succinic Acid SCHEMBL7192904 0.84 ALDH1A1 (0.36) TDP1TSHRALDH1A1CYP1A2CYP2D6
Acetic Acid SCHEMBL7192906 0.84 ALDH1A1 (0.36) HIF1ATDP1GAATSHRALDH1A1
Iodide SCHEMBL23853413 0.79 HTT (0.39) HIF1AACHETDP1TRAP1
Iodide SCHEMBL7193531 0.77 ACHE (0.38) HIF1AACHEGAAALDH1A1CYP1A2
Bromide SCHEMBL7196672 0.77 HRH3 (0.39) HIF1AACHETDP1SLC6A4MEN1
SCHEMBL29991623 0.76 HIF1A (0.64) HIF1ATDP1TSHRALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624173-B2 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS DOW CHEMICAL CO (US) 2003-04-09 EP disclosed
EP-0624173-B1 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS DOW CHEMICAL CO (US) 1997-04-02 EP disclosed
EP-0624173-A1 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS. DOW CHEMICAL CO (US) 1994-11-17 EP disclosed
US-5360886-A Alklyphenylphosphine or phosphonium catalyst THE DOW CHEMICAL COMPANY (US) 1994-11-01 US disclosed
US-5310853-A Epoxy resins THE DOW CHEMICAL COMPANY (US) 1994-05-10 US disclosed
WO-1993015126-A1 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS THE DOW CHEMICAL COMPANY (US) 1993-08-05 WO disclosed
US-5202407-A Phosphonium or phosphine catalyst having at least three alkylphenyl groups attached to phosphorus atom THE DOW CHEMICAL COMPANY (US) 1993-04-13 US disclosed