Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 7/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197345 | 0.83 | MCHR1 (0.38) | LIPGMCHR1TAAR1HTR6CYP2D6 | |
| SCHEMBL10153396 | 0.67 | TAAR1 (0.48) | MCHR1TAAR1HTR6SLC6A2SLC6A4 | |
| SCHEMBL16100563 | 0.66 | CXCR4 (0.34) | LIPGHTR2CHTR2A | |
| SCHEMBL10095064 | 0.65 | P2RX7 (0.45) | LIPGHTR2CHTR2A | |
| SCHEMBL10095057 | 0.65 | PDCD1 (0.41) | MCHR1HTR6CYP2D6HTR2CHTR2A | |
| SCHEMBL5880518 | 0.62 | NR1H4 (0.44) | — | |
| SCHEMBL839815 | 0.61 | HTR2A (0.50) | MCHR1HTR2CHTR2A | |
| SCHEMBL29539173 | 0.61 | HTR2A (0.50) | MCHR1HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL20139551 | 0.60 | HTR2A (0.49) | MCHR1HTR2CHTR2A | |
| SCHEMBL24176784 | 0.60 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294700-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000631-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |