Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817899 | 0.89 | TDP1 (0.50) | PRKCATDP1ARGAAALDH1A1 | |
| SCHEMBL19257812 | 0.88 | TDP1 (0.52) | PRKCATDP1ARGAAALDH1A1 | |
| SCHEMBL16684801 | 0.83 | ALDH1A1 (0.47) | PRKCATDP1ARGAAALDH1A1 | |
| SCHEMBL8362346 | 0.81 | PRKCA (0.55) | PRKCATDP1ALDH1A1LMNAPRKCE | |
| SCHEMBL14185499 | 0.81 | PRKCA (0.39) | PRKCALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL19257811 | 0.81 | PRKCA (0.50) | PRKCATDP1ARPRKCEPRKCQ | |
| SCHEMBL29032605 | 0.80 | TDP1 (0.48) | PRKCATDP1ARGAAALDH1A1 | |
| SCHEMBL3505846 | 0.80 | PRKCA (0.58) | PRKCAALDH1A1LMNAPRKCEPRKCQ | |
| Ethylene SCHEMBL11104304 | 0.80 | PRKCA (0.50) | PRKCATDP1ALDH1A1LMNACYP3A4 | |
| SCHEMBL10796873 | 0.80 | PRKCA (0.58) | PRKCAALDH1A1LMNAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579981-B1 | Treating herpes virus | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2003-06-17 | — | — | US | disclosed |