SCHEMBL19257812

SCHEMBL19257812

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nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
PRKCA P17252 4/20 0.43
AR P10275 1/20 0.42
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.40
GAA P10253 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
HRH1 P35367 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11817899 0.92 TDP1 (0.50) TDP1PRKCAARLMNATSHR
SCHEMBL19257811 0.92 PRKCA (0.50) TDP1PRKCAAR
Triacetin SCHEMBL3870 0.90 TDP1 (0.56) TDP1PRKCAARLMNATSHR
Triacetin SCHEMBL821340 0.90 TDP1 (0.56) TDP1PRKCAARLMNATSHR
SCHEMBL7758842 0.89 PRKCA (0.47) TDP1PRKCAARLMNATSHR
SCHEMBL18652575 0.89 TDP1 (0.47) TDP1PRKCAARLMNATSHR
SCHEMBL8362220 0.89 PRKCA (0.47) TDP1PRKCAARLMNATSHR
SCHEMBL7197347 0.88 PRKCA (0.44) TDP1PRKCAARLMNAGAA
Triacetin SCHEMBL8012678 0.88 TDP1 (0.54) TDP1PRKCAARLMNATSHR
Triacetin SCHEMBL16445622 0.88 TDP1 (0.54) TDP1PRKCAARLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170233337-A1 NON-IONIC AMPHIPHILES AND METHODS OF MAKING THE SAME ARCHER DANIELS MIDLAND CO (IL) 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233337-A1 NON-IONIC AMPHIPHILES AND METHODS OF MAKING THE SAME PNLIP, FFAR4, SPTLC2 TDP1 2837/4885PRKCA 1665/4885AR 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.