Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195422 | 0.89 | GPBAR1 (0.43) | ARMEN1KMT2AGPBAR1 | |
| SCHEMBL3486294 | 0.86 | GRIN1 (0.47) | ARGPBAR1 | |
| SCHEMBL7196165 | 0.83 | AR (0.44) | ARGPBAR1 | |
| SCHEMBL7196166 | 0.83 | AR (0.44) | ARGPBAR1 | |
| SCHEMBL6839046 | 0.83 | AKR1B10 (0.49) | GPBAR1SRD5A2 | |
| SCHEMBL6839045 | 0.83 | AKR1B10 (0.49) | GPBAR1SRD5A2 | |
| SCHEMBL15259496 | 0.82 | AR (0.61) | ARGPBAR1 | |
| SCHEMBL7193192 | 0.82 | AR (0.61) | ARGPBAR1 | |
| SCHEMBL867595 | 0.82 | AR (0.61) | ARGPBAR1 | |
| SCHEMBL2545024 | 0.82 | AR (0.61) | ARGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134828-A1 | Composition and method for increasing in vivo androgen concentration | ROBERTS WILLIAM J (US) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134828-A1 | Composition and method for increasing in vivo androgen concentration | SHBG, CYP21A2, CYP19A1 | AR 6/4885MEN1 580/4885KMT2A 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.