SCHEMBL7198147

SCHEMBL7198147

FC=CC1(c2ccc(Cl)cc2)CC1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
KDM1A O60341 1/20 0.39
DRD2 P14416 1/20 0.37
SLC6A4 P31645 7/20 0.36
SLC6A3 Q01959 7/20 0.36
SLC6A2 P23975 2/20 0.33
LMNA P02545 1/20 0.33
CYP2A6 P11509 1/20 0.33
HDAC4 P56524 1/20 0.33
BACE1 P56817 1/20 0.33
HSD11B1 P28845 3/20 0.33
OPRM1 P35372 1/20 0.32
EEF2K O00418 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23270189 0.75 DRD2 (0.38) MAOAMAOBKDM1ADRD2SLC6A4
SCHEMBL9585274 0.75 SLC6A4 (0.37) MAOAMAOBKDM1ADRD2SLC6A4
SCHEMBL9585278 0.75 SLC6A4 (0.37) MAOAMAOBKDM1ADRD2SLC6A4
SCHEMBL23270188 0.75 DRD2 (0.38) MAOAMAOBKDM1ADRD2SLC6A4
SCHEMBL10726441 0.75 SLC6A4 (0.35) MAOAMAOBKDM1ADRD2SLC6A4
SCHEMBL20876286 0.74 SLC6A4 (0.40) MAOAMAOBKDM1ADRD2SLC6A4
SCHEMBL695920 0.74 HSD17B10 (0.41) MAOAMAOBKDM1ADRD2SLC6A4
SCHEMBL8582677 0.72 HDAC4 (0.42) DRD2SLC6A4SLC6A3SLC6A2HDAC4
SCHEMBL6232127 0.72 DRD2 (0.39) MAOAMAOBKDM1ADRD2SLC6A4
SCHEMBL6233881 0.72 DRD2 (0.39) MAOAMAOBKDM1ADRD2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030135075-A1 Process and intermediate compounds for preparation of pesticidal fluoroolefin compounds WOOD WILLIAM WAKEFIELD (US) 2003-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030135075-A1 Process and intermediate compounds for preparation of pesticidal fluoroolefin compounds DDT, AHR, CYP2F1 MAOA 573/4885MAOB 519/4885KDM1A 934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.