Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.36 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620974 | 0.91 | HSD11B1 (0.41) | HSD17B10DRD2HDAC4SLC6A4SLC6A3 | |
| SCHEMBL6498103 | 0.91 | HDAC4 (0.44) | HSD17B10DRD2HDAC4SLC6A4SLC6A3 | |
| SCHEMBL10879701 | 0.90 | SLC6A4 (0.47) | HDAC4SLC6A4SLC6A3HSD11B1SLC6A2 | |
| SCHEMBL27594932 | 0.86 | DRD2 (0.55) | HSD17B10DRD2HDAC4SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL28029079 | 0.85 | DRD2 (0.53) | HSD17B10DRD2HDAC4SLC6A4SLC6A3 | |
| SCHEMBL13540015 | 0.83 | OPRM1 (0.51) | SLC6A4HSD11B1LMNAKMT2A | |
| SCHEMBL28800669 | 0.81 | MAOA (0.42) | HSD17B10DRD2HDAC4SLC6A4SLC6A3 | |
| SCHEMBL7113804 | 0.78 | MAOA (0.40) | HSD17B10DRD2HDAC4HSD11B1MAOA | |
| SCHEMBL1832213 | 0.78 | NPC1 (0.37) | — | |
| SCHEMBL12020373 | 0.78 | MAOA (0.44) | HSD17B10DRD2HDAC4SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009114173-A1 | AZABICYCLO [3. 2. I] OCTYL DERIVATIVES AS 11 BETA-HSDL MODULATORS | EXELIXIS, INC. (US) | 2009-09-17 | — | — | WO | claimed |
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | claimed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | claimed |
| US-5430060-A | Aldose reductase inhibitor | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | claimed |
| EP-0469887-B1 | Acetamide derivatives | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | claimed |
| EP-0469887-A1 | Acetamide derivatives | ZENECA LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| EP-0024172-B1 | ANTITUMOR AND IMMUNOSUPPRESSIVE 4-CARBAMOYLIMIDAZOLIUM-5-OLATE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-11 | — | — | EP | claimed |
| US-4317825-A | WATER SOLUBILITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-02 | — | — | US | claimed |
| EP-0024172-A1 | Antitumor and immunosuppressive 4-carbamoylimidazolium-5-olate derivatives, pharmaceutical composition and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-02-25 | — | — | EP | claimed |
| US-20240317686-A1 | RORyT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2024-09-26 | — | — | US | disclosed |
| EP-4273129-A1 | RORgammaT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| EP-4273129-A1 | RORgammaT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143771-A1 | RORγT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-07-07 | — | — | WO | disclosed |
| WO-2022143771-A1 | RORγT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-07-07 | — | — | WO | disclosed |
| EP-0179788-A1 | PESTICIDES. | NAT RES DEV (GB) | 1986-05-07 | — | — | EP | disclosed |
| EP-0161921-A2 | Improvements relating to pesticides | BTG INTERNATIONAL LIMITED (GB) | 1985-11-21 | — | — | EP | disclosed |
| WO-1985004651-A1 | IMPROVEMENTS RELATING TO PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-24 | — | — | WO | disclosed |
| US-RE30634-E | INSECTICIDES | SHELL OIL COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4079149-A | INSECTICIDES | SHELL OIL COMPANY (US) | 1978-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240317686-A1 | RORyT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | RORC, RORB, RORA | HSD17B10 583/4885DRD2 4433/4885HDAC4 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.