Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22361952 | 0.91 | SLC6A3 (0.46) | SLC6A4SLC6A3DRD2SLC6A2HDAC4 | |
| SCHEMBL22361954 | 0.91 | SLC6A4 (0.42) | SLC6A4SLC6A3DRD2SLC6A2LMNA | |
| SCHEMBL20876275 | 0.90 | SLC6A3 (0.49) | SLC6A4SLC6A3DRD2SLC6A2HDAC4 | |
| SCHEMBL695920 | 0.77 | HSD17B10 (0.41) | SLC6A4SLC6A3DRD2SLC6A2MAOA | |
| SCHEMBL20876288 | 0.77 | SLC6A3 (0.39) | SLC6A4SLC6A3SLC6A2MAOAMAOB | |
| SCHEMBL20876290 | 0.77 | CYP2A6 (0.36) | OPRM1CYP2A6 | |
| SCHEMBL20876280 | 0.77 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2OPRM1 | |
| SCHEMBL498413 | 0.76 | OPRL1 (0.50) | MAOAMAOBOPRM1 | |
| SCHEMBL7198147 | 0.74 | MAOA (0.39) | SLC6A4SLC6A3DRD2SLC6A2MAOA | |
| SCHEMBL9585278 | 0.74 | SLC6A4 (0.37) | SLC6A4SLC6A3DRD2SLC6A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200267977-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| EP-3692019-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2020-08-12 | — | — | EP | disclosed |
| CN-111183133-A | Microbicidal picolinamide derivatives | 先正达参股股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| WO-2019068812-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200267977-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | PRF1, CASP1, FPR1 | SLC6A4 3476/4885SLC6A3 3866/4885DRD2 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.