Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 3/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198582 | 0.90 | AR (0.46) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL6933335 | 0.87 | MEN1 (0.50) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL7119414 | 0.81 | AR (0.51) | MEN1MAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6933340 | 0.76 | PYGL (0.50) | MEN1MAPTKMT2AALDH1A1HTT | |
| SCHEMBL6431578 | 0.76 | PYGL (0.53) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL6933328 | 0.75 | PYGL (0.57) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7123016 | 0.75 | ALDH1A1 (0.44) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL12950801 | 0.69 | CRHBP (0.51) | MEN1KMT2AALDH1A1CRHBPCRHR2 | |
| SCHEMBL7119418 | 0.69 | AR (0.49) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL6433721 | 0.68 | SLC6A4 (0.57) | MEN1MAPTKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6590118-B1 | Used in treatment of and/or prevention of diabetes, especially non-insulin dependent diabetes (Type 2 diabetes) | NOVO NORDISK A/S (DK) | 2003-07-08 | — | — | US | disclosed |