Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.58 |
| ▸ | EDNRB | P24530 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194249 | 0.81 | PTGS2 (0.44) | PTGS2KMT2ATP53KDM4E | |
| SCHEMBL7173940 | 0.81 | PTGS2 (0.46) | PTGS2EDNRBEDNRAKMT2ATP53 | |
| SCHEMBL3016461 | 0.81 | PTGS2 (0.46) | PTGS2EDNRBEDNRAKMT2ATP53 | |
| SCHEMBL7149516 | 0.80 | PTGS2 (0.46) | PTGS2EDNRBEDNRAKMT2ATP53 | |
| SCHEMBL29415408 | 0.71 | PTGS2 (0.61) | PTGS2EDNRBEDNRAKMT2AALDH1A1 | |
| SCHEMBL937206 | 0.71 | PTGS2 (0.61) | PTGS2EDNRBEDNRAKMT2AALDH1A1 | |
| SCHEMBL28543127 | 0.71 | CA2 (0.44) | PTGS2 | |
| SCHEMBL2447766 | 0.69 | PTGS2 (0.64) | PTGS2ALDH1A1KDM4EMAOALOX | |
| Hydrochloric Acid SCHEMBL7352630 | 0.69 | PTGS2 (0.59) | PTGS2EDNRBEDNRAKMT2AALDH1A1 | |
| SCHEMBL8798623 | 0.69 | PTGS2 (0.68) | PTGS2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339428-A1 | INHALATION OF NITRIC OXIDE | AGA AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002040052-A1 | INHALATION OF NITRIC OXIDE | AGA AB (SE) | 2002-05-23 | — | — | WO | disclosed |