SCHEMBL7199165

SCHEMBL7199165

O=C(O)c1ccc(S(=O)(=O)Cl)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 5/20 0.46
HSD17B10 Q99714 4/20 0.46
CYP2C9 P11712 2/20 0.46
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
WDR5 P61964 1/20 0.43
FABP4 P15090 2/20 0.42
FABP5 Q01469 2/20 0.42
FABP3 P05413 1/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42
LDHA P00338 2/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
ATIC P31939 1/20 0.42
ALDH1A1 P00352 4/20 0.41
ALOX15 P16050 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1339684 0.89 NR4A1 (0.50) MCL1HSD17B10CYP2C9NR4A1NR4A2
SCHEMBL29472291 0.83 CYP2D6 (0.50) MCL1HSD17B10CYP2C9NR4A1NR4A2
SCHEMBL7190686 0.83 CYP2D6 (0.50) MCL1HSD17B10CYP2C9NR4A1NR4A2
SCHEMBL9479929 0.82 LDHA (0.37) MCL1HSD17B10CYP2C9FABP4FABP5
SCHEMBL9165551 0.82 ALDH1A1 (0.48) HSD17B10LDHATSHRALDH1A1CA1
SCHEMBL7199578 0.81 MCL1 (0.63) MCL1HSD17B10CYP2C9NR4A1NR4A2
SCHEMBL22672642 0.80 CA1 (0.49) HSD17B10NR4A2KDM4EHPGDTSHR
SCHEMBL28798 0.79 NR4A1 (0.65) HSD17B10CYP2C9NR4A1NR4A2NR4A3
SCHEMBL29406630 0.79 NR4A1 (0.65) HSD17B10CYP2C9NR4A1NR4A2NR4A3
SCHEMBL30838413 0.79 NR4A1 (0.65) HSD17B10CYP2C9NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 MCL1 3029/4885HSD17B10 1952/4885CYP2C9 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.