Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647782 | 0.92 | THRB (0.53) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL7195094 | 0.88 | MAPT (0.50) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL6831102 | 0.86 | MAPT (0.45) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL6643264 | 0.85 | MAPT (0.50) | MAPTALDH1A1KMT2ALMNATDP1 | |
| SCHEMBL16448843 | 0.83 | L3MBTL1 (0.51) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL6643012 | 0.82 | HTT (0.54) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL6644659 | 0.81 | NPC1 (0.55) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL6643855 | 0.80 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AMCL1MEN1 | |
| SCHEMBL6644222 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL6649926 | 0.79 | OGA (0.49) | MAPTALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |