Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189152 | 0.84 | NQO1 (0.44) | HTTHIF1AKMT2AMAPTHSD17B10 | |
| SCHEMBL7062464 | 0.81 | HIF1A (0.63) | HTTHIF1AARKMT2AMAPT | |
| SCHEMBL31462812 | 0.80 | ESR1 (0.42) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL3618538 | 0.80 | HPGD (0.39) | HTTHIF1AARKMT2AMAPT | |
| SCHEMBL818909 | 0.79 | MAPT (0.39) | KMT2AMAPTGAALMNAKDM4E | |
| SCHEMBL10595211 | 0.79 | MAPK1 (0.41) | ARKMT2AMAPTLMNAHSD17B10 | |
| SCHEMBL16553424 | 0.79 | HIF1A (0.56) | HTTHIF1AARKMT2AMAPT | |
| SCHEMBL7636232 | 0.76 | CYP3A4 (0.34) | HIF1AARKMT2AMAPTHSD17B10 | |
| SCHEMBL2137216 | 0.76 | ALDH1A1 (0.68) | HIF1AKMT2AMAPTGAALMNA | |
| SCHEMBL8057791 | 0.75 | ESR1 (0.50) | HIF1AARKMT2ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6623823-B1 | Radiopaque polymer coating | ETHICON, INC. | 2003-09-23 | — | — | US | disclosed |
| EP-1016424-A1 | Radiopaque polymer coating | ETHICON, INC. (US) | 2000-07-05 | — | — | EP | disclosed |