Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7197153 | 0.88 | HTR2C (0.31) | OXTR | |
| Hydrochloric Acid SCHEMBL7203972 | 0.78 | CYP2D6 (0.38) | OXTR | |
| Hydrochloric Acid SCHEMBL7200948 | 0.78 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL7196058 | 0.76 | KDM4E (0.36) | TSHR | |
| Hydrochloric Acid SCHEMBL7203525 | 0.76 | CYP2A6 (0.38) | TSHR | |
| Fluoride Ion SCHEMBL1130161 | 0.74 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL1685525 | 0.69 | OXTR (0.32) | OXTR | |
| Hydrochloric Acid SCHEMBL31317947 | 0.69 | OXTR (0.32) | OXTR | |
| Hydrochloric Acid SCHEMBL16654327 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL5607395 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776909-B1 | HIGH DENSITY ETHYLENE POLYMER AND METHOD FOR PRODUCING THE SAME | ASAHI CHEMICAL IND (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5973083-A | HIGH IMPACT RESISTANCE AND HIGH STIFFNESS, EXCELLENT MOLDABILITY, HIGH MELT FLOWABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0776909-A1 | HIGH-DENSITY ETHYLENIC POLYMER AND PROCESS FOR PRODUCING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-06-04 | — | — | EP | disclosed |