Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875298 | 0.98 | HRH1 (0.48) | HRH1HTR2ATBXAS1SIGMAR1GRM2 | |
| SCHEMBL7320028 | 0.92 | HRH1 (0.50) | HRH1HTR2ATBXAS1SIGMAR1GRM2 | |
| SCHEMBL21913847 | 0.84 | HRH1 (0.46) | HRH1HTR2ASRCMTNR1AMTNR1B | |
| SCHEMBL10933645 | 0.84 | SRC (0.44) | HRH1HTR2ASIGMAR1SRC | |
| SCHEMBL8019892 | 0.82 | RIPK1 (0.44) | SRC | |
| SCHEMBL9426203 | 0.82 | SLC6A3 (0.47) | HRH1HTR2ACYP19A1 | |
| SCHEMBL11077118 | 0.80 | CCR1 (0.39) | TBXAS1SRC | |
| SCHEMBL10717648 | 0.80 | CYP19A1 (0.42) | CYP19A1 | |
| SCHEMBL7075226 | 0.79 | RIPK1 (0.47) | SRC | |
| SCHEMBL972987 | 0.79 | RIPK1 (0.47) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106445-A1 | COMPOUNDS AND METHODS FOR CONTROLLING BACTERIAL VIRULENCE | QSI PHARMA A/S (DK) | 2003-12-24 | — | — | WO | disclosed |