Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | GCG | P01275 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720542 | 0.96 | CYP2C19 (0.37) | CYP2C19ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL720006 | 0.87 | TP53 (0.34) | CYP2C19ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL719479 | 0.82 | GCG (0.46) | ALDH1A1MAPTHPGDALOX15KMT2A | |
| SCHEMBL716552 | 0.81 | NPC1 (0.40) | CYP2C19ALDH1A1MAPTKMT2AVKORC1 | |
| SCHEMBL719941 | 0.78 | TEAD4 (0.39) | CYP2C19ALDH1A1HPGDHDAC6TEAD4 | |
| SCHEMBL2669983 | 0.77 | GCG (0.41) | CYP2C19KMT2AHDAC6GCGSLC22A12 | |
| SCHEMBL3110628 | 0.77 | GCG (0.38) | CYP2C19ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL719577 | 0.76 | GCGR (0.37) | MAPTHDAC6GCGABL1RIN1 | |
| SCHEMBL719970 | 0.76 | CYP2C19 (0.49) | CYP2C19ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL718671 | 0.75 | MAOB (0.38) | MAPTTEAD4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | CYP2C19 946/4885ALDH1A1 504/4885MAPT 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.