Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.42 |
| ▸ | KDM5A | P29375 | 6/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490180 | 0.91 | LMNA (0.41) | KDM4CKDM4EDCTPP1P2RX3PPARG | |
| SCHEMBL6490213 | 0.90 | MRGPRX4 (0.40) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL6501562 | 0.86 | NR4A2 (0.57) | MRGPRX4PPARGNR4A2NR4A1NR4A3 | |
| SCHEMBL6498704 | 0.84 | P2RX3 (0.45) | P2RX3MRGPRX4PPARG | |
| SCHEMBL6494714 | 0.82 | KDM4C (0.44) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL6495987 | 0.82 | PIK3C2B (0.41) | P2RX3MRGPRX4PPARGALOX5APSLC16A3 | |
| SCHEMBL6491685 | 0.82 | FABP3 (0.46) | MRGPRX4ALOX5AP | |
| SCHEMBL6172911 | 0.81 | PPARG (0.48) | DCTPP1MRGPRX4PPARGNR4A2 | |
| SCHEMBL7200058 | 0.81 | FABP3 (0.48) | MRGPRX4ALOX5AP | |
| SCHEMBL6488333 | 0.80 | MRGPRX4 (0.43) | KDM4CKDM5ADCTPP1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | KDM4C 443/4885KDM5A 682/4885KDM5B 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.