Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 5/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200058 | 0.90 | FABP3 (0.48) | PIK3C2BFABP3FABP4FABP5PIK3CB | |
| SCHEMBL7200216 | 0.90 | PIK3C2B (0.41) | PIK3C2BFABP3FABP4FABP5DCTPP1 | |
| SCHEMBL6498814 | 0.89 | S1PR1 (0.39) | PIK3C2BDCTPP1S1PR1PRKXACVR1 | |
| SCHEMBL6489346 | 0.87 | MRGPRX4 (0.46) | MRGPRX4PPARG | |
| SCHEMBL7193408 | 0.85 | PIK3C2B (0.42) | PIK3C2BDCTPP1PIK3CBMRGPRX4PPARG | |
| SCHEMBL6487408 | 0.83 | DCTPP1 (0.38) | DCTPP1S1PR1PRKXACVR1S1PR5 | |
| SCHEMBL6499333 | 0.83 | BCL2 (0.50) | PIK3C2B | |
| SCHEMBL7659283 | 0.83 | PIK3C2B (0.47) | PIK3C2BDCTPP1PIK3CBPPARG | |
| SCHEMBL6490528 | 0.82 | DCTPP1 (0.42) | DCTPP1MRGPRX4PPARG | |
| SCHEMBL6489201 | 0.81 | DCTPP1 (0.40) | DCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |