Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | THPO | P40225 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15323851 | 0.73 | — | — | |
| SCHEMBL16034334 | 0.68 | KDM4E (0.32) | KDM4EMAPTTSHRAPLNRFFAR3 | |
| SCHEMBL8356444 | 0.67 | MEN1 (0.33) | MAPK1TP53HIF1ANPC1LMNA | |
| SCHEMBL23979209 | 0.64 | MEN1 (0.32) | MAPK1TP53HIF1ANPC1LMNA | |
| SCHEMBL4328440 | 0.63 | HTT (0.30) | HTT | |
| SCHEMBL9577220 | 0.63 | — | — | |
| SCHEMBL19226095 | 0.63 | APLNR (0.30) | APLNR | |
| SCHEMBL15840883 | 0.63 | APLNR (0.33) | MAPK1TP53HIF1ANPC1LMNA | |
| SCHEMBL2175960 | 0.61 | MAPK1 (0.34) | MAPK1TP53HIF1ANPC1LMNA | |
| SCHEMBL20599606 | 0.61 | SMN1; SMN2 (0.36) | SMN1; SMN2NPSR1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030131548-A1 | Material for plastic lens, production process of the material, composition for plastic lens, plastic lens obtained by curing the composition, and production process of the plastic lens | SHOWA DENKO K.K. (JP) | 2003-07-17 | — | — | US | disclosed |
| WO-2001096909-A2 | MATERIAL FOR PLASTIC LENS, PRODUCTION PROCESS OF THE MATERIAL, COMPOSITION FOR PLASTIC LENS, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION, AND PRODUCTION PROCESS OF THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2001-12-20 | — | — | WO | disclosed |